Seroatlas · Protein domains
Ras family
PF00071
Definition
Includes sub-families Ras, Rab, Rac, Ral, Ran, Rap Ypt1 and more. Shares P-loop motif with GTP_EFTU, arf and myosin_head. See [pfam:PF00009] [pfam:PF00025], [pfam:PF00063]. As regards Rab GTPases, these are important regulators of vesicle formation, motility and fusion. They share a fold in common with all Ras GTPases: this is a six-stranded beta-sheet surrounded by five alpha-helices PMID:11387043.
137 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
Download CSV (137 proteins: gene, accession, name)
- AGAP1
- AGAP2
- AGAP3
- ARHGAP35
- CDC42
- CPLANE2
- CRACR2A
- DIRAS1
- DIRAS2
- DIRAS3
- DNAJC27
- ERAS
- GEM
- HRAS
- IFT27
- KRAS
- MRAS
- NKIRAS1
- NKIRAS2
- NRAS
- RAB10
- RAB11A
- RAB11B
- RAB12
- RAB13
- RAB14
- RAB15
- RAB17
- RAB18
- RAB19
- RAB1A
- RAB1B
- RAB1C
- RAB20
- RAB21
- RAB22A
- RAB23
- RAB24
- RAB25
- RAB26
- RAB27A
- RAB27B
- RAB28
- RAB29
- RAB2A
- RAB2B
- RAB30
- RAB31
- RAB32
- RAB33A
- RAB33B
- RAB34
- RAB35
- RAB36
- RAB37
- RAB38
- RAB39A
- RAB39B
- RAB3A
- RAB3B
- RAB3C
- RAB3D
- RAB40A
- RAB40AL
- RAB40B
- RAB40C
- RAB41
- RAB42
- RAB43
- RAB44
- RAB4A
- RAB4B
- RAB5A
- RAB5B
- RAB5C
- RAB6A
- RAB6B
- RAB6C
- RAB6D
- RAB7A
- RAB7B
- RAB8A
- RAB8B
- RAB9A
- RAB9B
- RABL2A
- RABL2B
- RAC1
- RAC2
- RAC3
- RALA
- RALB
- RAN
- RAP1A
- RAP1B
- RAP1BL
- RAP2A
- RAP2B
- RAP2C
- RASD1
- RASD2
- RASEF
- RASL10A
- RASL10B
- RASL11A
- RASL11B
- RASL12
- REM1
- REM2
- RERG
- RERGL
- RHEB
- RHEBL1
- RHOA
- RHOB
- RHOBTB1
- RHOBTB2
- RHOBTB3
- RHOC
- RHOD
- RHOF
- RHOG
- RHOH
- RHOJ
- RHOQ
- RHOT1
- RHOT2
- RHOU
- RHOV
- RIT1
- RIT2
- RND1
- RND2
- RND3
- RRAD
- RRAS
- RRAS2
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