Seroatlas · Human Serome Atlas

RAP1BL

Ras-related protein Rap-1b-like protein

Also known as: RP1BL_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NIZ1
Gene: RAP1BL
Canonical length: 184 aa

OverviewNCBI Gene

No narrative summary is available for RAP1BL in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

184 residues, UniProt reviewed canonical sequence.

>A6NIZ1|RAP1BL
     1  MREYKLVVLG SRGVGKSALT VQFVQGIFVE KYDPTIEDSY REQVEVDAQQ CMLEILDTAG
    61  TEQFTAMRDL YMKNGQGFAL VYSITAQSTF NDLQDLREQI LRVKDTDDVP MILVGNKCDL
   121  EDERVVGKEQ GQNLARQWNN CAFLESSAKS KINVNEIFYD LVRQINRKTP VPGKARKKSS
   181  CQLL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against RAP1BL can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.29

OntologyGO

Biological processes

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads RAP1BL as an antibody target. Whether an autoantibody or antibody against RAP1BL could matter depends on whether native RAP1BL is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

RAP1BL is annotated at the cell surface, where native RAP1BL is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label RAP1BL as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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