RAB1C
Putative Ras-related protein Rab-1C
Also known as: RAB1C_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for RAB1C in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
201 residues, UniProt reviewed canonical sequence.
>Q92928|RAB1C
1 MNPGYDCLFK LLLIGDSGVG KSCLLLRFAD DPYTESYIST IGVDFKIQTI ELDGKTIKLQ
61 IWDTAGQERF WTITSSYYRG AHGFLVVYDV TDQESYANVK QWLQEIDRHA SENVNKLLVG
121 NKSDLTTKKV VDNTTAKEFA DSLGIPFLET SAKNATNVEQ AFMTMAAEIK KQMGPGAASG
181 GERPNLKIDS TPVKPAGGGC CLocalizationUniProt · AlphaFold · HPA
Whether an antibody against RAB1C can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Intracellular
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.33
OntologyGO
Biological processes
- autophagosome assembly
- endoplasmic reticulum to Golgi vesicle-mediated transport
- Golgi organization
- intracellular protein transport
- positive regulation of glycoprotein metabolic process
- virion assembly
Molecular functions
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads RAB1C as an antibody target. Whether an autoantibody or antibody against RAB1C could matter depends on whether native RAB1C is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
RAB1C is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label RAB1C as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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