Seroatlas · Protein domains
SH3 domain
PF00018
Definition
SH3 (Src homology 3) domains are often indicative of a protein involved in signal transduction related to cytoskeletal organisation. First described in the Src cytoplasmic tyrosine kinase [swissprot:P12931]. The structure is a partly opened beta barrel.
108 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
Download CSV (108 proteins: gene, accession, name)
- ABI1
- ABI2
- ABL1
- ABL2
- AHI1
- ARHGAP12
- ARHGAP9
- ARHGEF16
- ARHGEF26
- ARHGEF37
- ARHGEF4
- ARHGEF5
- BCAR1
- BLK
- BTK
- CD2AP
- CRK
- CRKL
- CSK
- DLG1
- DLG2
- DLG3
- DLG4
- DNMBP
- DOCK1
- DOCK5
- EPS8
- EPS8L1
- EPS8L2
- EPS8L3
- FCHSD2
- FGR
- FNBP1
- FNBP1L
- FRK
- FYN
- GRAP
- GRAP2
- GRAPL
- GRB2
- HCK
- HCLS1
- ITK
- ITSN1
- ITSN2
- LCK
- LYN
- MATK
- MPP1
- MPP7
- MYO1E
- MYO1F
- NCF1
- NCF1B
- NCF1C
- NCF2
- NCF4
- NCK1
- NCK2
- NCKIPSD
- NGEF
- NOXA1
- NOXO1
- NPHP1
- OSTF1
- PLCG1
- PLCG2
- PPP1R13B
- PRMT2
- PSTPIP1
- PTK6
- RASA1
- SGSM3
- SH3BP4
- SH3D19
- SH3GL1
- SH3GL3
- SH3PXD2A
- SH3PXD2B
- SH3RF1
- SH3RF2
- SH3RF3
- SH3TC1
- SH3TC2
- SKAP2
- SLA
- SLA2
- SORBS1
- SORBS2
- SORBS3
- SPATA13
- SPTA1
- SPTAN1
- SRC
- SRGAP1
- SRGAP2
- SRGAP3
- STAC
- STAC3
- STAM
- STAM2
- TEC
- TP53BP2
- TRIO
- TRIP10
- TXK
- VAV1
- YES1
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