C2H2-type zinc-finger domain-containing protein
IPR050752
Definition
This family of proteins includes transcription factors that are involved in various developmental and regulatory processes. Members of this family are characterized by the presence of C2H2-type zinc-finger domains, which facilitate DNA binding and allow these proteins to regulate gene expression. Functions attributed to these proteins include roles in embryonic central nervous system development, neuronal fate specification, muscle structure, and transcriptional regulation of specific genes. Some family members are implicated in processes such as cell proliferation, migration, inflammation, and embryonic development. Additionally, certain proteins within this family have been associated with the modulation of signaling pathways and the maintenance of pluripotency in stem cells.
41 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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