Seroatlas · Human Serome Atlas

ZNF658B

Zinc finger protein 658B

Also known as: Z658B_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q4V348
Gene: ZNF658B
Canonical length: 819 aa

OverviewNCBI Gene

No narrative summary is available for ZNF658B in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

819 residues, UniProt reviewed canonical sequence.

>Q4V348|ZNF658B
     1  MMNLEKNFDK TTLFNHMRTD KRGKCSDLNE YGTSCDKTTA VEYNKVHMAM THYECNERGI
    61  NFSRKSPLTQ SQRTITGWSA FESNKCEENF SQSSAHIVHQ KTQAGDKFGE HNECTDALYQ
   121  KLDFTAHQRI HTDFTAHQKF YLSDEHGKCR KSFYWKAHLI QHERPHSGEK TYQYEECAKS
   181  FCSSSHPIQH PGTYVGFKLY ECNECGKAFC QNSNLSKHLR IHTKEKPCDN NGCGRSYKSP
   241  LIGHQKTDAE MELCGGSEYG KTSHLKGHQR ILMGEKPYEC IECGKTFSKT SHLRAHQRIH
   301  TGEKPYECVE CEKTFSHKTH LSVHQRVHTG EKPYECNDCG KSFTYNSALR AHQRIHTGEK
   361  PYECSDCEKT FAHNSALRAH HRIHTGEKPY ECNECGRSFA HISVLKAHQR IHTREKPYEC
   421  NECGRSFTYN SALRAHQRIH TGRKPYECSD CEKTFAHNSA LKIHQRIHTG EKPYKCNECE
   481  KTFAHNSALR AHQNIHTGEK LYECSECGKT FFQKTRLSTH RRIHTGEKPY ECSKCGKTFS
   541  QKSYLSGHER IHTGEKPYEC NVCGKTFVYK AALIVHQRIH TGEKPYECNE CGKTFSQRTH
   601  LCAHQRIHTG EKPYECNECG KTFADNSALR AHHRIHTGEK PYECNDCGKT FSKTSHLRAH
   661  LRTRSGEKPY ECSECGKTFS EKSYVSAHQR VHTGEKPYEC NVCGKPFAHN STLRVHQRIH
   721  TGEKSYECND CGKTFSQKSH LSAHQRIHTG EKPYECNECG KAFAQNSTLR VHQRIHTGEK
   781  PYECDECGKT FVRKAALRVH HTRMHTREKT LACNGFGKS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ZNF658B can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.48

OntologyGO

Biological processes

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ZNF658B as an antibody target. Whether an autoantibody or antibody against ZNF658B could matter depends on whether native ZNF658B is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ZNF658B is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ZNF658B as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...