SPRY-associated domain

Definition

PRY is a 50-60 amino acids domain associated with SPRY domains, adjacent to its N-terminal. PRY and SPRY domains are structurally very similar and consist of a beta sandwich fold [[cite:PMID:15353551],[cite:PMID:23139046],[cite:PMID:17189197]]. Distant homologues are domains in butyrophilin/marenostrin/pyrin, evolutionarily more ancient than SPRY/B30.2 counterpart.

44 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (44 proteins: gene, accession, name)

• BSPRY
• BTN1A1
• BTN2A1
• BTN2A2
• BTN2A3P
• BTN3A1
• BTN3A3
• BTNL3
• BTNL8
• BTNL9
• ERMAP
• MEFV
• RFPL1
• RFPL2
• RFPL3
• RFPL4A
• RFPL4AL1
• RFPL4B
• RNF39
• TRIM10
• TRIM11
• TRIM14
• TRIM15
• TRIM16
• TRIM16L
• TRIM21
• TRIM25
• TRIM26
• TRIM27
• TRIM35
• TRIM38
• TRIM39
• TRIM41
• TRIM50
• TRIM58
• TRIM60
• TRIM62
• TRIM68
• TRIM69
• TRIM7
• TRIM72
• TRIM75
• TRIML1
• TRIML2