Olfactory receptor 51/52/56-like
IPR050402
Definition
The olfactory receptor family is comprised of G-protein coupled receptors with a primary function as odorant receptors. These receptors detect and bind specific molecules from the environment, initiating a signal transduction pathway that results in the perception of smell. Activation of these receptors typically leads to the elevation of intracellular Ca2, cAMP, and the activation of protein kinases such as PKA and MAPK3/MAPK1. Some members of the family, such as Olfactory receptor 51E2, respond to short-chain fatty acids PMID:36922591 and L-lactate PMID:28542639, influencing physiological processes such as melanocyte function, blood pressure regulation, and cell proliferation and migration, particularly in retinal pigment epithelial cells.
62 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
Download CSV (62 proteins: gene, accession, name)
- OR51A2
- OR51A4
- OR51A7
- OR51B2
- OR51B4
- OR51B5
- OR51B6
- OR51C1
- OR51D1
- OR51E1
- OR51E2
- OR51F1
- OR51F2
- OR51G1
- OR51G2
- OR51H1
- OR51I1
- OR51I2
- OR51J1
- OR51L1
- OR51M1
- OR51Q1
- OR51S1
- OR51T1
- OR51V1
- OR52A1
- OR52A4P
- OR52A5
- OR52B2
- OR52B4
- OR52B6
- OR52D1
- OR52E1
- OR52E2
- OR52E4
- OR52E5
- OR52E6
- OR52E8
- OR52H1
- OR52I1
- OR52I2
- OR52J3
- OR52K1
- OR52K2
- OR52L1
- OR52L2P
- OR52M1
- OR52N1
- OR52N2
- OR52N4
- OR52N5
- OR52P1
- OR52R1
- OR52W1
- OR52Z1P
- OR56A1
- OR56A3
- OR56A4
- OR56A5
- OR56B1
- OR56B2
- OR56B4
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