Seroatlas · Human Serome Atlas

OR56B2

Olfactory receptor 56B2

Also known as: O56B2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NGI1
Gene: OR56B2
Canonical length: 316 aa

OverviewNCBI Gene

No narrative summary is available for OR56B2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

316 residues, UniProt reviewed canonical sequence.

>Q8NGI1|OR56B2
     1  MVLQELRDSN SSKFQVSEFI LMGFPGIHSW QHWLSLPLAL LYLLALSANI LILIIINKEA
    61  ALHQPMYYFL GILAMADIGL ATTIMPKILA ILWFNAKTIS LLECFAQMYA IHCFVAMESS
   121  TFVCMAIDRY VAICRPLRYP SIITESFVFK ANGFMALRNS LCLISVPLLA AQRHYCSQNQ
   181  IEHCLCSNLG VTSLSCDDRR INSINQVLLA WTLMGSDLGL IILSYALILY SVLKLNSPEA
   241  ASKALSTCTS HLILILFFYT VIIVISITRS TGMRVPLIPV LLNVLHNVIP PALNPMVYAL
   301  KNKELRQGLY KVLRLE

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR56B2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.28

OntologyGO

Biological processes

cellular response to lipid

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR56B2 as an antibody target. Whether an autoantibody or antibody against OR56B2 could matter depends on whether native OR56B2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR56B2 is annotated at the cell surface, where native OR56B2 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR56B2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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