Seroatlas · Human Serome Atlas

OR52Z1P

Olfactory receptor 52Z1P

Also known as: O52Z1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0C646
Gene: OR52Z1P
Canonical length: 298 aa

OverviewNCBI Gene

No narrative summary is available for OR52Z1P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

298 residues, UniProt reviewed canonical sequence.

>P0C646|OR52Z1P
     1  MGIPGLEGLH TWISIPFSFM YIVAVAGNIF LIFLIMTERS LHEPMYLFLS MLASADFLLA
    61  TAAAPKVLAI LWFHSMDISF GSCVSQMFFI HFIFVAESAI LLAMAFDRYV AICYPLRYTI
   121  LTSSAVRKIG IAAVVRSFFI CCPFIFLVYR LTYCGRNIIP HSYCEHIARL ACGNINVNII
   181  YGLTVALLST GLDIVLIIIS YTMILHSVFQ ISSWAARFKA LSTCGSHICV IFMFYTPAFF
   241  SFLAHRFGGK TIPHHIHILV GSLYVLVPPM LNPIIYGVKT KQIKDRVILL FSPISVCC

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR52Z1P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.28

OntologyGO

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR52Z1P as an antibody target. Whether an autoantibody or antibody against OR52Z1P could matter depends on whether native OR52Z1P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR52Z1P is annotated at the cell surface, where native OR52Z1P is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR52Z1P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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