Seroatlas · Human Serome Atlas

OR51C1

Olfactory receptor OR51C1

Also known as: O51C1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A0A3B3IT45
Gene: OR51C1
Canonical length: 312 aa

OverviewNCBI Gene

No narrative summary is available for OR51C1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

312 residues, UniProt reviewed canonical sequence.

>A0A3B3IT45|OR51C1
     1  MGSNITSTSI IFLLTGVPGL EAFHTWISIP FCFLSVTALL GNSLILFATI TQPSLHEPMY
    61  YFLSMLSATD LGLSISTLVT MLSIFWFNVR EISFNACLSH MFFIKFFTVM ESSVLLAMAF
   121  DRFVAVSNPL RYAMILTDSR IAQIGVASVI RGLLMLTPMV ALLIRLSYCH SQVLHHSYCY
   181  HPDVMKLSCT DTRINSAVGL TAMFSTVGVD LLLILLSYVL IIRTVLSVAS PEERKETFST
   241  CVSHIVAFAI YYIPLISLSI VHRFGKQAPA YVHTMIANTY LLISPLMNPV IYSVKTKQIR
   301  RAVIKILHSK ET

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR51C1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.27

OntologyGO

Biological processes

cellular response to lipid

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR51C1 as an antibody target. Whether an autoantibody or antibody against OR51C1 could matter depends on whether native OR51C1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR51C1 is annotated at the cell surface, where native OR51C1 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR51C1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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