Seroatlas · Human Serome Atlas

OR52A4P

Olfactory receptor 52A4

Also known as: O52A4_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NMU1
Gene: OR52A4P
Canonical length: 304 aa

OverviewNCBI Gene

No narrative summary is available for OR52A4P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

304 residues, UniProt reviewed canonical sequence.

>A6NMU1|OR52A4P
     1  MALPITNGTL FMPFVLTFIG IPGFESVQCW IGIPFCATYV IALIGNSLLL IIIKSEPSLH
    61  EPMYIFLATL GATDISLSTS IVPKMLDIFW FHLPEIYFDA CLFQMWLIHT FQGIESGVLL
   121  AMALDRCVAI CYPLRRAIVF TRQLVTYIVV GVTLRPAILV IPCLLLIKCH LKLYRTKLIY
   181  HTYCERVALV KLATEDVYIN KVYGILGAFI VGGLDFIFIT LSYIQIFITV FHLPLKEARL
   241  KVFNTCIPHI YVFFQFYLLA FFFIFYSQIW ILYPIICTYH LVQSLPTGPT IPQPLYLWVK
   301  DQTH

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR52A4P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.3

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 2% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR52A4P as an antibody target. Whether an autoantibody or antibody against OR52A4P could matter depends on whether native OR52A4P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR52A4P is annotated at the cell surface, where native OR52A4P is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR52A4P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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