Seroatlas · Human Serome Atlas

OR52P1

Olfactory receptor 52P1

Also known as: O52P1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NH57
Gene: OR52P1
Canonical length: 321 aa
Protein class: Predicted membrane proteins

OverviewNCBI Gene

No narrative summary is available for OR52P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

321 residues, UniProt reviewed canonical sequence.

>Q8NH57|OR52P1
     1  MESPNHTDVD PSVFFLLGIP GLEQFHLWLS LPVCGLGTAT IVGNITILVV VATEPVLHKP
    61  VYLFLCMLST IDLAASVSTV PKLLAIFWCG AGHISASACL AQMFFIHAFC MMESTVLLAM
   121  AFDRYVAICH PLRYATILTD TIIAHIGVAA VVRGSLLMLP CPFLIGRLNF CQSHVILHTY
   181  CEHMAVVKLA CGDTRPNRVY GLTAALLVIG VDLFCIGLSY ALSAQAVLRL SSHEARSKAL
   241  GTCGSHVCVI LISYTPALFS FFTHRFGHHV PVHIHILLAN VYLLLPPALN PVVYGVKTKQ
   301  IRKRVVRVFQ SGQGMGIKAS E

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR52P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.29
Highest tissue expression: 0.2 nTPM

Expression across tissuesHPA

Tissue

bone marrow: 0.2 nTPM
appendix: 0.1 nTPM
epididymis: 0.1 nTPM
adipose tissue: 0 nTPM
adrenal gland: 0 nTPM
breast: 0 nTPM

Single-cell type

adipocytes: 0 nCPM
adrenal cortex cells: 0 nCPM
adrenal medulla cells: 0 nCPM
alveolar cells type 1: 0 nCPM
alveolar cells type 2: 0 nCPM
astrocytes: 0 nCPM

Immune cell

naive B-cell: 0.1 nTPM
basophil: 0 nTPM
classical monocyte: 0 nTPM
eosinophil: 0 nTPM
gdT-cell: 0 nTPM
intermediate monocyte: 0 nTPM

Brain region

hypothalamus: 0.9 nTPM
medulla oblongata: 0.8 nTPM
basal ganglia: 0.6 nTPM
cerebral cortex: 0.6 nTPM
spinal cord: 0.5 nTPM
amygdala: 0.4 nTPM

OntologyGO

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR52P1 as an antibody target. Whether an autoantibody or antibody against OR52P1 could matter depends on whether native OR52P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR52P1 is annotated at the cell surface, where native OR52P1 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR52P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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