Seroatlas · Human Serome Atlas

OR51H1

Olfactory receptor 51H1

Also known as: O51H1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NH63
Gene: OR51H1
Canonical length: 302 aa

OverviewNCBI Gene

No narrative summary is available for OR51H1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

302 residues, UniProt reviewed canonical sequence.

>Q8NH63|OR51H1
     1  MTNLNASQAN HRNFILTGIP GTPDKNPWLA FPLGFLYTLT LLGNGTILAV IKVEPSLHEP
    61  TYYFLSILAL TDVSLSMSTL PSMLSIYWFN APQIVFDACI MQMFFIHVFG IVESGVLVSM
   121  AFDRFVAIRN PLHYVSILTH DVIRKTGIAV LTRAVCVVFP VPFLIKCLPF CHSNVLSHSY
   181  CLHQNMMRLA CASTRINSLY GLIVVIFTLG LDVLLTLLSY VLTLKTVLGI VSRGERLKTL
   241  STCLSHMSTV LLFYVPFMGA ASMIHRFWEH LSPVVHMVMA DIYLLLPPVL NPIVYSVKTK
   301  QI

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR51H1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.28

OntologyGO

Biological processes

cellular response to lipid

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR51H1 as an antibody target. Whether an autoantibody or antibody against OR51H1 could matter depends on whether native OR51H1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR51H1 is annotated at the cell surface, where native OR51H1 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR51H1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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