Collagen triple helix repeat
IPR008160
Definition
Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The sequence is predominantly repeats of the G-X-Y and the polypeptide chains form a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxyproline. Collagens are post-translationally modified by proline hydroxylase to form the hydroxyproline residues. Defective hydroxylation is the cause of scurvy [[cite:PMID:11158359], [cite:PMID:21726633], [cite:PMID:1720597]]. Members of this family belong to the collagen superfamily PMID:8240831. Some of them are not involved in connective tissue structure but share the same triple helical structure.
78 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
Download CSV (78 proteins: gene, accession, name)
- ADIPOQ
- C1QA
- C1QB
- C1QC
- C1QL1
- C1QL2
- C1QL3
- C1QTNF1
- C1QTNF2
- C1QTNF3
- C1QTNF5
- C1QTNF6
- C1QTNF7
- C1QTNF8
- C1QTNF9
- C1QTNF9B
- CCBE1
- COL10A1
- COL11A1
- COL11A2
- COL12A1
- COL13A1
- COL14A1
- COL15A1
- COL16A1
- COL17A1
- COL18A1
- COL19A1
- COL1A1
- COL1A2
- COL20A1
- COL21A1
- COL22A1
- COL23A1
- COL24A1
- COL25A1
- COL26A1
- COL27A1
- COL28A1
- COL2A1
- COL3A1
- COL4A1
- COL4A2
- COL4A3
- COL4A4
- COL4A5
- COL4A6
- COL5A1
- COL5A2
- COL5A3
- COL6A1
- COL6A2
- COL6A3
- COL6A5
- COL6A6
- COL7A1
- COL8A1
- COL8A2
- COL9A1
- COL9A2
- COL9A3
- COLEC10
- COLEC11
- COLEC12
- COLQ
- EMID1
- EMILIN1
- FCN1
- FCN2
- GLDN
- MARCO
- MBL2
- MSR1
- OTOL1
- SCARA3
- SCARA5
- SFTPD
- WDR33
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