Seroatlas · Protein domains
PMP-22/EMP/MP20/Claudin
IPR004031
Definition
This family of evolutionarily related integral membrane proteins includes PMP22, EMP, claudins and voltage-gated calcium channel gamma subunits, many of which perform diverse functions at specialised cell-cell contacts PMID:24665403. Family members from vertebrates and invertebrates are highly divergent.
45 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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