Kinesin-like protein
IPR027640
Definition
This entry includes kinesin heavy chain and kinesin-like proteins, which are members of the kinesin superfamily (also known as KIFs). KIFs constitute 15 kinesin families PMID:15479732. They are important molecular motors that directionally transport various cargos, including membranous organelles, protein complexes and mRNAs PMID:19773780. Kinesin [[cite:PMID:8542443], [cite:PMID:2142876], [cite:PMID:14732151]] is a microtubule-associated force-producing protein that play a role in organelle transport. The kinesin motor activity is directed toward the microtubule's plus end. Kinesin is an oligomeric complex composed of two heavy chains and two light chains. The maintenance of the quaternary structure does not require interchain disulphide bonds.
32 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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