Seroatlas · Protein domains
Zinc finger, C3HC4 type (RING finger)
PF00097
Definition
The C3HC4 type zinc-finger (RING finger) is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C where X is any amino acid PMID:8804826. Many proteins containing a RING finger play a key role in the ubiquitination pathway PMID:10500182.
37 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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