C-type lectin and snaclec domain-containing protein
IPR050111
Definition
This family of proteins includes C-type lectins and snaclecs, which are known for their carbohydrate recognition domains. They are involved in a variety of biological processes, including cell-cell adhesion, immune response, and pathogen recognition. Members of this family can bind to specific carbohydrate structures on cell surfaces, leading to cell agglutination or modulation of signaling pathways. Some proteins in this family are involved in hemostasis, interfering with platelet aggregation or the coagulation cascade. They may act as anticoagulants by binding to coagulation factors or platelet receptors, or as procoagulants by inducing platelet aggregation such as snaclecs PMID:20350564. The functions of these proteins are often calcium-dependent and can be influenced by the presence of specific sugars or metal ions.
28 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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