Non-receptor tyrosine kinases involved in cell signaling
IPR050198
Definition
This family of proteins includes non-receptor tyrosine kinases that play crucial roles in various cellular processes. They are involved in signal transduction pathways that regulate immune responses, cell growth, survival, differentiation, cytoskeletal remodeling, cell adhesion, and migration. These proteins are activated by cell surface receptors and are essential for both innate and adaptive immunity. They also participate in the regulation of B-cell and T-cell receptor signaling, contributing to the development and function of lymphocytes. Additionally, they mediate responses to growth factors, cytokines, and environmental stresses, influencing processes like platelet activation, vascular development, and osteoclast maturation.
25 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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