Ras association (RalGDS/AF-6) domain

Definition

RasGTP effectors (in cases of AF6, canoe and RalGDS); putative RasGTP effectors in other cases. Recent evidence (not yet in MEDLINE) shows that some RA domains do NOT bind RasGTP. Predicted structure PMID:8987396 similar to that determined PMID:9253406, and that of the RasGTP-binding domain of Raf kinase.

27 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (27 proteins: gene, accession, name)

• AFDN
• ARAP1
• ARAP2
• ARAP3
• ARHGAP20
• DGKQ
• MYO9A
• MYO9B
• PLCE1
• RADIL
• RALGDS
• RAPGEF2
• RAPGEF6
• RASIP1
• RASSF1
• RASSF2
• RASSF3
• RASSF4
• RASSF5
• RASSF6
• RASSF7
• RGL1
• RGL2
• RGL3
• RIN1
• RIN2
• SNX27