IPT domain

Definition

The IPT (Ig-like, plexins, transcription factors) domain has an immunoglobulin like fold PMID:10390613. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. The Ron tyrosine kinase receptor shares with the members of its subfamily (Met and Sea) a unique functional feature: the control of cell dissociation, motility, and invasion of extracellular matrices (scattering) PMID:8816464.

30 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (30 proteins: gene, accession, name)

• CAMTA1
• CAMTA2
• EBF1
• EBF2
• EBF3
• EBF4
• EXOC2
• MET
• MST1R
• NFAT5
• NFATC1
• NFATC2
• NFATC3
• NFATC4
• NFKB1
• NFKB2
• PKHD1
• PKHD1L1
• PLXNA1
• PLXNA2
• PLXNA3
• PLXNA4
• PLXNB1
• PLXNB2
• PLXNB3
• PLXNC1
• PLXND1
• REL
• RELA
• RELB