Carcinoembryonic antigen-related cell adhesion
IPR050831
Definition
The CEA family proteins are predominantly involved in cell adhesion processes, with members functioning in homophilic and heterophilic interactions that are calcium-independent. They belong to the immunoglobulin superfamily and play roles in various biological processes including immune response regulation, insulin action, angiogenesis, and tumor progression. Some members are implicated in maintaining the integrity of the tectorial membrane for proper hearing, while others are involved in phagocytosis, metabolic regulation, and the transport of bile acids. Additionally, certain proteins within the family are associated with pregnancy, such as the pregnancy-specific beta-1-glycoproteins, which may have roles in immune modulation during gestation.
21 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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