CD225/Dispanin family
IPR007593
Definition
This family represents a set of transmembrane proteins including various interferon-induced transmembrane proteins, synapse differentiation-inducing gene protein 1, and tumor suppressor candidate 5 and homologues. Interferon-induced transmembrane protein 1 (also known as human leukocyte antigen CD225) regulates vesicular membrane fusion events and is essential for different physiological processes such as interferon induced cell growth suppression, neurotransmision and metabolism [[cite:PMID:7559564], [cite:PMID:22363774], [cite:PMID:33518406]].
16 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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