C9JQL5
Putative dispanin subfamily A member 2d
Also known as: DSA2D_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for C9JQL5 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
133 residues, UniProt reviewed canonical sequence.
>C9JQL5|C9JQL5
1 MNHTVQTFFS PVNSGQPPNY EMLKEEHKVA VLGVPHNPAP PTSTVIHIRS KTSVPHHVVW
61 SLFNTLFMNP CCLGFIAFAY SVKSRDRKMV GNVTGAQAYA STTKCLNIWA LILGILMTIL
121 LIIIPVLIFQ AHRLocalizationUniProt · AlphaFold · HPA
Whether an antibody against C9JQL5 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Cell surface
- Secreted
- No
- Transmembrane segments
- 2
- Mean surface accessibility (rSASA)
- 0.54
OntologyGO
Biological processes
- defense response to virus
- host-mediated suppression of symbiont invasion
- negative regulation of viral genome replication
- response to interferon-alpha
- response to interferon-beta
- response to type II interferon
- type I interferon-mediated signaling pathway
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads C9JQL5 as an antibody target. Whether an autoantibody or antibody against C9JQL5 could matter depends on whether native C9JQL5 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
C9JQL5 is annotated at the cell surface, where native C9JQL5 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.
Annotation status
The present source text does not explicitly label C9JQL5 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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