Snf7 family
IPR005024
Definition
Snf7 family members are small coil-coiled proteins that share protein sequence similarity with budding yeast Snf7, which is part of the ESCRT-III complex that is required for endosome-mediated trafficking via multivesicular body (MVB) formation and sorting PMID:15086794. Proteins in this entry also includes human CHMPs (charged multivesicular body proteins), budding yeast Did4/Did2,Arabidopsisvacuolar protein sorting-associated proteins and the archaeanSulfolobus acidocaldariuscell division protein B which is a component required for cell division, forming polymers with segregating nucleoids PMID:18987308.
12 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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