HD/PDEase domain

Definition

This entry represents the HD domain, which is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity. It also represents a related phosphodiesterase (PDEase) domain that is found in eukaryotic 3',5'-cGMP phosphodiesterase ([ec:3.1.4.17]), which is located in photoreceptor outer segments and it is light activated, playing a pivotal role in signal transduction PMID:11008484.

23 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (23 proteins: gene, accession, name)

• HDDC2
• HDDC3
• PDE10A
• PDE11A
• PDE1A
• PDE1B
• PDE1C
• PDE2A
• PDE3A
• PDE3B
• PDE4A
• PDE4B
• PDE4C
• PDE5A
• PDE6A
• PDE6B
• PDE6C
• PDE7A
• PDE7B
• PDE8A
• PDE8B
• PDE9A
• SAMHD1