Endonuclease/Exonuclease/phosphatase family

Definition

This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling PMID:10838565. This family includes: AP endonuclease proteins [ec:4.2.99.18] e.g [swissprot:P27695], DNase I proteins [ec:3.1.21.1] e.g. [swissprot:P24855], Synaptojanin an inositol-1,4,5-trisphosphate phosphatase [ec:3.1.3.56] [swissprot:O43426], Sphingomyelinase [ec:3.1.4.12] [swissprot:P11889] and Nocturnin [swissprot:O35710].

17 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (17 proteins: gene, accession, name)

• ANGEL1
• ANGEL2
• APEX1
• APEX2
• CNOT6
• CNOT6L
• DNASE1
• DNASE1L1
• DNASE1L2
• DNASE1L3
• EEPD1
• NOCT
• O00370
• PDE12
• SMPD2
• SMPD3
• TDP2