Seroatlas · Protein domains
Endonuclease/exonuclease/phosphatase
IPR005135
Definition
This domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular signalling PMID:10838565. Proteins this domain is found in include: AP endonuclease proteins ([ec:4.2.99.18]), DNase I proteins ([ec:3.1.21.1]), Synaptojanin an inositol-1,4,5-trisphosphate phosphatase ([ec:3.1.3.56]) and Sphingomyelinase ([ec:3.1.4.12]).
17 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
Loading the interactive Seroatlas explorer...