P-type ATPase, cytoplasmic domain N
PF13246
Definition
This entry represents the cytoplasmic domain N found in P-type ATPase , including phospholipid-transporting ATPases, calcium-transporting ATPases, and sodium-potassium ATPases [[cite:PMID:21653810],[cite:PMID:1384045]].The cytoplasmic loops of the P-type ATPases form three separate modules, commonly named the A, P and N-domains [[cite:PMID:15448704],[cite:PMID:28443028]]. The N-domain comprises the nucleotide binding site PMID:15448704. This domain forms a seven-stranded antiparallel beta-sheet with two additional beta-strands forming a hairpin and five alpha-helices PMID:28443028.
32 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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