DnaJ C terminal domain

Definition

This family consists of the C terminal region of the DnaJ protein. It is always found associated with [pfam:PF00226] and [pfam:PF00684]. DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress. The two C-terminal domains CTDI and CTDII, both incorporated in this family are necessary for maintaining the J-domains in their specific relative positions PMID:22011374. Structural analysis of PDB:1nlt shows that PF00684 is nested within this DnaJ C-terminal region PMID:14656432.

9 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (9 proteins: gene, accession, name)

• DNAJA1
• DNAJA2
• DNAJA3
• DNAJA4
• DNAJB1
• DNAJB11
• DNAJB13
• DNAJB4
• DNAJB5