Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

Definition

This domain is responsible for the high-affinity binding of calcium ions. This domain contains post-translational modifications of many glutamate residues by Vitamin K-dependent carboxylation to form gamma-carboxyglutamate (Gla).

12 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (12 proteins: gene, accession, name)

• F10
• F2
• F7
• F9
• GAS6
• PROC
• PROS1
• PROZ
• PRRG1
• PRRG2
• PRRG3
• PRRG4