Striated Muscle Structural and Regulatory Protein
IPR050964
Definition
This family of proteins is involved in the structural organization and functional regulation of striated muscle cells. They are associated with the myofibrillar M band and A bands, where they interact with major components such as myosin, actin, and titin. These interactions are important for maintaining the integrity of the sarcomere structure and for modulating the activity of muscle contraction. Some family members are also implicated in cardiac function, potentially influencing muscle contraction and the conduction systems of the heart. Additionally, certain proteins within this family may play a role in myofibrillogenesis, the process of forming the contractile threads in muscle cells.
11 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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