POU domain transcription factor
IPR050255
Definition
The POU transcription factor family is characterized by its involvement in the regulation of gene expression in various developmental and differentiation processes. Members of this family are known to bind specific DNA sequences, often referred to as octamer motifs, to modulate the transcription of target genes. They play pivotal roles in neurodevelopment, sensory neuron specification, and the maintenance of stem cell pluripotency. Additionally, they are implicated in the differentiation of specific cell types in the anterior pituitary and the regulation of immune and neural functions in mucosal epithelial tissues. The POU factors are also associated with the regulation of apoptosis, cell fate decisions during embryogenesis, and the development of the auditory system.
17 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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