Golgi associated RAB2 interactor protein-like, Rab2B-binding domain

Definition

This domain is found in Golgi-associated RAB2 interactor proteins and it is likely a Rab2B-binding domain [[cite:PMID:34714330], [cite:PMID:26209634], [cite:PMID:28930687]]. Some members included in this entry, such as GAR1A/B andGAR2, are RAB2B effector proteins required for accurate acrosome formation and normal male fertility [[cite:PMID:34714330], [cite:PMID:29025071]]. GARIL5 is a Rab2B effector protein which promotes cytosolic DNA-induced innate immune responses PMID:28930687 and GARI-L4 is a RAB2B effector protein required for the compacted Golgi morphology PMID:26209634. This domain is also found in TASOR2, whose function is unknown.

9 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (9 proteins: gene, accession, name)

• GARIN1A
• GARIN1B
• GARIN2
• GARIN3
• GARIN4
• GARIN5A
• GARIN5B
• GARIN6
• TASOR2