Nuclear transport factor 2, eukaryote

Definition

Ran ([interpro:IPR002041]) is an evolutionary conserved member of the Ras superfamily of small GTPases that regulates all receptor-mediated transport between the nucleus and the cytoplasm. Import receptors bind their cargos in the cytoplasm where the concentration of RanGTP is low and release their cargos in the nucleus where the concentration of RanGTP is high PMID:12019565. Export receptors respond to Ran GTP in the opposite manner.

8 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (8 proteins: gene, accession, name)

• G3BP1
• G3BP2
• NUTF2
• NXF1
• NXF2
• NXF3
• NXT1
• NXT2