Seroatlas · Protein domains
TRIM protein coiled-coil region
PF25600
Definition
This entry represents a long helical region connecting domains in TRIM proteins such as TRIM16, TRIM29, TRIM25, TRIM 65, TRIM47, TRIM8 and TRIM14. The TRIM Coiled-Coil (TRIM_CC) domain is a long helical region found in Tripartite Motif (TRIM) proteins, which are part of the RING finger E3 ubiquitin ligase family PMID:23630998. This domain plays a crucial role in protein-protein interactions, particularly in the dimerization and self-association of TRIM proteins PMID:31406497.
8 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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