Transcription factor S-II (TFIIS), central domain

Definition

Transcription elongation by RNA polymerase II is regulated by the general elongation factor TFIIS. This factor stimulates RNA polymerase II to transcribe through regions of DNA that promote the formation of stalled ternary complexes. TFIIS is composed of three structural domains, termed I, II, and III. The two C-terminal domains (II and III), this domain and [pfam:PF01096] are required for transcription activity PMID:8855225.

7 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (7 proteins: gene, accession, name)

• DIDO1
• PHF3
• SPOCD1
• TCEA1
• TCEA2
• TCEA3
• TCEANC