Rel homology DNA-binding domain

Definition

Proteins containing the Rel homology domain (RHD) are eukaryotic transcription factors. The RHD is composed of two structural domains. This is the N-terminal DNA-binding domain that is similar to that found in P53. The C-terminal domain has an immunoglobulin-like fold (See [pfam:PF16179]) that functions as a dimerisation domain [[cite:PMID:7830764],[cite:PMID:17869269]].

10 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (10 proteins: gene, accession, name)

• NFAT5
• NFATC1
• NFATC2
• NFATC3
• NFATC4
• NFKB1
• NFKB2
• REL
• RELA
• RELB