Olfactory G-protein coupled receptor 1
IPR050939
Definition
The olfactory receptor family is comprised of G-protein coupled receptors that are primarily involved in the detection of odorants. These receptors are integral membrane proteins that initiate a signal transduction cascade upon binding to specific molecules, leading to a sensory perception of smell. Each receptor is tuned to recognize a diverse array of chemical compounds, allowing for a broad range of olfactory sensations. Some members of the family have been shown to play roles beyond olfaction, such as in wound-healing processes and hair growth, indicating a multifunctional nature. The activation of these receptors typically involves G proteins, which can trigger various intracellular pathways, including the elevation of intracellular Ca(2+), activation of cAMP-dependent pathways, and phosphorylation of MAPKs.
19 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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