Seroatlas · Human Serome Atlas

OR11H7

Olfactory receptor 11H7

Also known as: O11H7_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q8NGC8
Gene
OR11H7
Canonical length
314 aa
Protein class
Predicted membrane proteins

OverviewNCBI Gene

No narrative summary is available for OR11H7 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

314 residues, UniProt reviewed canonical sequence.

>Q8NGC8|OR11H7
     1  MNNSQISTVT QFVLLGFPGP WKIQIIFFSM ILLVYIFTLT GNMAIICAVR WDHRLHTPMY
    61  VLLANFSFLE IWYVTCTVPN MLVNFFSKTK TISFSGCFTQ FHFFFSLGTT ECFFLCVMAY
   121  DRYLAICHPL HYPSIMTGQL CGILVSLCWL IGFLGHSISI FFIFQLPFCG PNIIDHFLCD
   181  VDPLMALSSA PTHIIGHVFH SVSSLFINLT MVYILGSYTL VLRTVLQVPS SAGWQKAIST
   241  CGSHLVVVSL FYGAIMLMYV SPTPGNSVAM HKLITLIYSV VTPVLNPLIY SLRNKDMKYA
   301  LHHVFCGMRI IQRS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR11H7 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Cell surface
Secreted
No
Transmembrane segments
7
Mean surface accessibility (rSASA)
0.27
Highest tissue expression
0.3 nTPM

Expression across tissuesHPA

Tissue

  • testis: 0.3 nTPM
  • gallbladder: 0.1 nTPM
  • heart muscle: 0.1 nTPM
  • skin: 0.1 nTPM
  • adipose tissue: 0 nTPM
  • adrenal gland: 0 nTPM

Single-cell type

  • megakaryocyte-erythroid progenitors: 0.2 nCPM
  • adipocytes: 0 nCPM
  • adrenal cortex cells: 0 nCPM
  • adrenal medulla cells: 0 nCPM
  • alveolar cells type 1: 0 nCPM
  • alveolar cells type 2: 0 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • basal ganglia: 0.2 nTPM
  • cerebral cortex: 0.2 nTPM
  • spinal cord: 0.2 nTPM
  • white matter: 0.2 nTPM
  • amygdala: 0.1 nTPM
  • hippocampal formation: 0.1 nTPM

OntologyGO

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR11H7 as an antibody target. Whether an autoantibody or antibody against OR11H7 could matter depends on whether native OR11H7 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR11H7 is annotated at the cell surface, where native OR11H7 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR11H7 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/OR11H7. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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