Beta/Gamma-Crystallin
IPR050252
Definition
The beta/gamma-crystallin family comprises proteins that are primarily known as the dominant structural components of the vertebrate eye lens. These proteins are characterized by a two-domain beta-structure, which is folded into four highly similar Greek key motifs. The crystallins in this family contribute to the transparency and refractive properties of the lens, essential for proper vision. Some members of the family may also have roles beyond the eye lens, as suggested by their presence in other tissues and involvement in processes such as the integrity and function of auditory nuclei.
15 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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