Serine/threonine-protein kinases, AGC
IPR050236
Definition
The protein family includes serine/threonine kinases that play key roles in various cellular processes such as cell cycle progression, cell structure, proliferation, apoptosis, migration, adhesion, and transcription regulation. They are involved in signaling pathways that control organ size, tumor suppression, and cellular responses to stress and external stimuli. Members of this family phosphorylate a range of substrates, modulating their activity and localization, which is crucial for maintaining cellular integrity and responding to environmental changes. They are also implicated in the regulation of metabolic pathways, immune responses, and developmental processes.
9 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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