Seroatlas · Protein domains
E2F-DP heterodimerization region
IPR037241
Definition
The E2F transcription factors associated with the corresponding domain of the DP transcription factor forming an heterodimer fold with the N-terminal long helices of both chains forming a parallel coiled coil and their C-terminal folded β-hairpins interlocking together in a β-sandwich. This complex binds the C terminus of retinoblastoma protein PMID:16360038.
9 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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