Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily

Definition

This superfamily represents the C-terminal domain of the phosphatidylinositol-4-phosphate 4/5-kinases (PIP4K/PIP5K). It has a 2-layer sandwich structure PMID:9753329. PIP4/5K catalyses the formation of phosphoinositol-4,5-bisphosphate via the phosphorylation of phosphatidylinositol-4-phosphate a precursor in the phosphoinositide signalling pathway PMID:9535851.

9 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (9 proteins: gene, accession, name)

• PIKFYVE
• PIP4K2A
• PIP4K2B
• PIP4K2C
• PIP5K1A
• PIP5K1B
• PIP5K1C
• PIP5KL1
• PIPSL