Histidine kinase/HSP90-like ATPase domain

Definition

This domain is found in several ATP-binding proteins, including: histidine kinase PMID:15157101, DNA gyrase B, topoisomerases PMID:15105144, heat shock protein HSP90 [[cite:PMID:15292259], [cite:PMID:14718169], [cite:PMID:15217611]], phytochrome-like ATPases and DNA mismatch repair proteins. The fold of this domain consists of two layers, α/β, which contains an 8-stranded mixed β-sheet.

13 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (13 proteins: gene, accession, name)

• BCKDK
• HSP90AA1
• HSP90AA2P
• HSP90AB1
• HSP90AB4P
• HSP90B1
• PDK1
• PDK2
• PDK3
• PDK4
• TOP2A
• TOP2B
• TRAP1