Pointed domain

Definition

The highly conserved PNT (or Pointed) domain is found within a subset of the Ets transcription factors, including mammalian Ets-1, Ets-2, Erg, Fli-1, GABPalpha, and Tel, as well as Drosophila Pnt-P2 and Yan. The PNT domain is structurally related to the larger group of SAM domains through a common tertiary arrangement of four α-helices. A role in protein-protein association has been established for the PNT domain [[cite:PMID:10828014], [cite:PMID:15351649]].

11 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (11 proteins: gene, accession, name)

• EHF
• ELF3
• ELF5
• ERG
• ETS1
• ETS2
• ETV6
• ETV7
• FLI1
• GABPA
• SPDEF