Seroatlas · Protein domains

Phosphorylated immunoreceptor signalling ITAM

IPR003110

Definition

Phosphorylated immunoreceptor signalling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases PMID:7594458. Motif may be dually phosphorylated on tyrosine that links antigen receptors to downstream signalling machinery.

8 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (8 proteins: gene, accession, name)

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