PR domain zinc finger protein 2, PR domain

Definition

This domain is found in PR domain zinc protein 2 from humans (PRDM2) and similar proteins from animals. PRDM2 is a histone methyltransferase that functions as a DNA-binding transcription factor. It contains a PR (PRDI-BF1 and RIZ1 homology) domain, which is a distinct SET domain, that is responsible for its catalytic activity (this entry). This domain displays a typical SET fold consisting mainly of short beta-strands and intervening loops including a pseudo-knot at the C terminus PMID:18082620.

17 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (17 proteins: gene, accession, name)

• MECOM
• PRDM1
• PRDM10
• PRDM11
• PRDM12
• PRDM13
• PRDM14
• PRDM15
• PRDM16
• PRDM2
• PRDM4
• PRDM5
• PRDM6
• PRDM7
• PRDM8
• PRDM9
• ZNF408