ADAMTS cysteine-rich domain 2

Definition

This cysteine rich domain is found in a variety of ADAMTS peptidases (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) which is closely related to the ADAM family ([pfam:PF08516]) [[cite:PMID:8995297],[cite:PMID:10464288]]. Members of the ADAM-TS family have been implicated in a range of diseases [[cite:PMID:34268335],[cite:PMID:17265492],[cite:PMID:29885460]]. For instance, members of this family have been found to participate directly in processes in the central nervous system (CNS) such as the regulation of brain plasticity PMID:32150898.

19 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (19 proteins: gene, accession, name)

• ADAMTS1
• ADAMTS10
• ADAMTS12
• ADAMTS13
• ADAMTS14
• ADAMTS15
• ADAMTS16
• ADAMTS17
• ADAMTS18
• ADAMTS19
• ADAMTS2
• ADAMTS20
• ADAMTS3
• ADAMTS4
• ADAMTS5
• ADAMTS6
• ADAMTS7
• ADAMTS8
• ADAMTS9